Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 16/20 | 0.52 |
| ▸ | PGR | P06401 | 4/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | AR | P10275 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | MMP1 | P03956 | 14/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10889875 | 1.00 | NR3C1 (0.52) | NR3C1PGRHIF1ACYP3A4AR | |
| SCHEMBL10891515 | 0.92 | PGR (0.54) | NR3C1PGRCYP3A4ARSMN1; SMN2 | |
| SCHEMBL10427871 | 0.92 | PGR (0.54) | NR3C1PGRCYP3A4ARSMN1; SMN2 | |
| SCHEMBL10427872 | 0.92 | PGR (0.54) | NR3C1PGRCYP3A4ARSMN1; SMN2 | |
| SCHEMBL10891634 | 0.92 | NR3C1 (0.63) | NR3C1PGRHIF1ACYP3A4AR | |
| SCHEMBL10891645 | 0.92 | NR3C1 (0.63) | NR3C1PGRHIF1ACYP3A4AR | |
| SCHEMBL10893967 | 0.90 | NR3C1 (0.57) | NR3C1PGRCYP3A4ARSMN1; SMN2 | |
| SCHEMBL10893972 | 0.90 | NR3C1 (0.57) | NR3C1PGRCYP3A4ARSMN1; SMN2 | |
| SCHEMBL10427777 | 0.90 | NR3C1 (0.62) | NR3C1PGRCYP3A4ARSMN1; SMN2 | |
| SCHEMBL10888709 | 0.89 | NR3C1 (0.47) | NR3C1PGRCYP3A4ARMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4619922-A | 6α, 16α-dimethyl corticoids | SCHERING AKTIENGESELLSCHAFT (DE) | 1986-10-28 | — | — | US | disclosed |