Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 9/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.44 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | SLC15A2 | Q16348 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10890522 | 1.00 | TDP1 (0.44) | TDP1HPGDHSD17B10LMNAMAPT | |
| SCHEMBL9481794 | 0.91 | TDP1 (0.55) | TDP1HPGDHSD17B10LMNAMAPT | |
| SCHEMBL9481784 | 0.91 | TDP1 (0.55) | TDP1HPGDHSD17B10LMNAMAPT | |
| SCHEMBL10892443 | 0.86 | TDP1 (0.54) | TDP1HPGDHSD17B10LMNAMAPT | |
| SCHEMBL10892425 | 0.86 | TDP1 (0.54) | TDP1HPGDHSD17B10LMNAMAPT | |
| SCHEMBL10893628 | 0.84 | TDP1 (0.62) | TDP1HPGDHSD17B10LMNAMAPT | |
| SCHEMBL10893625 | 0.84 | TDP1 (0.62) | TDP1HPGDHSD17B10LMNAMAPT | |
| SCHEMBL10893639 | 0.84 | TDP1 (0.62) | TDP1HPGDHSD17B10LMNAMAPT | |
| SCHEMBL8867412 | 0.84 | TDP1 (0.53) | TDP1HPGDHSD17B10LMNAMAPT | |
| SCHEMBL8867421 | 0.84 | TDP1 (0.53) | TDP1HPGDHSD17B10LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4631274-A | MICROBIOCIDES | FUJISAWA PHARMCEUTICAL CO., LTD. (JP) | 1986-12-23 | — | — | US | disclosed |
| EP-0154354-A2 | New cephem compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-09-11 | — | — | EP | disclosed |