Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.44 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8867412 | 1.00 | TDP1 (0.53) | TDP1HSD17B10LMNAL3MBTL1PTGS1 | |
| SCHEMBL8868072 | 0.86 | TDP1 (0.58) | TDP1HSD17B10L3MBTL1PTGS1CTDSP1 | |
| SCHEMBL8868061 | 0.86 | TDP1 (0.58) | TDP1HSD17B10L3MBTL1PTGS1CTDSP1 | |
| SCHEMBL8867974 | 0.86 | TDP1 (0.68) | TDP1HSD17B10LMNAL3MBTL1PTGS1 | |
| SCHEMBL8867984 | 0.86 | TDP1 (0.68) | TDP1HSD17B10LMNAL3MBTL1PTGS1 | |
| SCHEMBL9481794 | 0.85 | TDP1 (0.55) | TDP1HSD17B10LMNAL3MBTL1CTDSP1 | |
| SCHEMBL9481784 | 0.85 | TDP1 (0.55) | TDP1HSD17B10LMNAL3MBTL1CTDSP1 | |
| SCHEMBL10890522 | 0.84 | TDP1 (0.44) | TDP1HSD17B10LMNAL3MBTL1CTDSP1 | |
| SCHEMBL10890519 | 0.84 | TDP1 (0.44) | TDP1HSD17B10LMNAL3MBTL1CTDSP1 | |
| SCHEMBL11417474 | 0.83 | TDP1 (0.44) | TDP1HSD17B10LMNAL3MBTL1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5594132-A | ANTIBIOTIC | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-14 | — | — | US | disclosed |
| US-5026695-A | Gram negative-gram positive microbiocides, oral adminis tration | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-06-25 | — | — | US | disclosed |
| US-4904652-A | 7-acylamino-3-substituted cephalosporanic acid derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-02-27 | — | — | US | disclosed |
| US-4462999-A | CEPHALOSPORINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-07-31 | — | — | US | disclosed |
| US-4409215-A | BACTERICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-10-11 | — | — | US | disclosed |
| EP-0029557-A2 | 7-Acylamino-3-substituted cephalosporanic acid derivatives, processes for their preparation and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-06-03 | — | — | EP | disclosed |