SCHEMBL10891237

SCHEMBL10891237

CN(C)C(C)(C)C(=O)c1ccc2c(c1)Sc1ccccc1S2

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.40
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
NOX1 Q9Y5S8 2/20 0.40
CYBB P04839 1/20 0.40
APP P05067 1/20 0.40
GAA P10253 1/20 0.40
ALOX15 P16050 1/20 0.40
SNCA P37840 1/20 0.40
NOX3 Q9HBY0 1/20 0.40
NOX4 Q9NPH5 1/20 0.40
LMNA P02545 2/20 0.39
MAPK1 P28482 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
BCHE P06276 5/20 0.37
KCNH2 Q12809 3/20 0.37
CYP1A2 P05177 2/20 0.37
CHRM2 P08172 2/20 0.37
HTR1A P08908 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19253126 0.80 NPC1 (0.35) MAPTLMNAL3MBTL1
SCHEMBL9511264 0.77 CES1 (0.52) MAPTMEN1KMT2ANOX1CYBB
SCHEMBL9510032 0.77 MAPT (0.41) MAPTMEN1KMT2ANOX1CYBB
SCHEMBL17559563 0.76 NOX1 (0.38) MAPTMEN1KMT2ANOX1CYBB
SCHEMBL17559561 0.76 NOX1 (0.36) MAPTMEN1KMT2ANOX1CYBB
SCHEMBL2129616 0.74 MAPT (0.65) MAPTMEN1KMT2ANOX1CYBB
SCHEMBL58163 0.74 CES1 (0.50) MEN1KMT2ATDP1CYP1A2CYP2D6
SCHEMBL19268226 0.74 BCHE (0.40) MAPTMEN1KMT2ANOX1CYBB
SCHEMBL30944690 0.72 PLEC (0.51) MAPTMEN1KMT2ANOX1CYBB
SCHEMBL2639219 0.72 PLEC (0.51) MAPTMEN1KMT2ANOX1CYBB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4582862-A QUICK-SETTING PRINTING INKS BASED ON ACRYLATED RESINS CIBA-GEIGY CORPORATION (US) 1986-04-15 US disclosed