Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 19/20 | 0.58 |
| ▸ | ADRB1 | P08588 | 13/20 | 0.58 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10889312 | 0.92 | ADRB3 (0.67) | ADRB3ADRB1 | |
| SCHEMBL10433623 | 0.89 | ADRB3 (0.67) | ADRB3ADRB1 | |
| SCHEMBL11184611 | 0.85 | ADRB3 (0.65) | ADRB3ADRB1 | |
| SCHEMBL10725397 | 0.84 | ADRB2 (0.59) | ADRB3ADRB1 | |
| SCHEMBL10725416 | 0.84 | ADRB2 (0.59) | ADRB3ADRB1 | |
| SCHEMBL10725426 | 0.84 | ADRB2 (0.59) | ADRB3ADRB1 | |
| SCHEMBL10727993 | 0.83 | ADRB3 (0.66) | ADRB3ADRB1 | |
| SCHEMBL10890639 | 0.82 | PNMT (0.48) | ADRB1 | |
| SCHEMBL10890383 | 0.81 | SLC2A1 (0.70) | ADRB3ADRB1SLC2A1 | |
| SCHEMBL19329740 | 0.81 | ADRB3 (0.53) | ADRB3ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4588749-A | ANTIOBESITY AND HYPOGLYCEMIC AGENTS | BEECHAM GROUP P.L.C. (GB) | 1986-05-13 | — | — | US | disclosed |
| EP-0040000-B1 | ARYLETHANOLAMINE DERIVATIVES, THEIR PREPARATION AND USE IN PHARMACEUTICAL COMPOSITIONS | BEECHAM GROUP PLC (GB) | 1983-10-12 | — | — | EP | disclosed |
| EP-0040000-A1 | Arylethanolamine derivatives, their preparation and use in pharmaceutical compositions | BEECHAM GROUP PLC (GB) | 1981-11-18 | — | — | EP | disclosed |