Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1539099 | 0.81 | FGFR1 (0.46) | MAPTHSD17B10NPC1RAB9AMEN1 | |
| SCHEMBL19848314 | 0.81 | ALDH1A1 (0.47) | MAPTHSD17B10NPC1RAB9AMEN1 | |
| SCHEMBL6536735 | 0.81 | PRPS1 (0.42) | MAPTHSD17B10TDP1NPC1RAB9A | |
| SCHEMBL10893089 | 0.81 | NPC1 (0.46) | MAPTHSD17B10TDP1NPC1RAB9A | |
| SCHEMBL623907 | 0.81 | MAPT (0.64) | MAPTHSD17B10TDP1NPC1RAB9A | |
| SCHEMBL11234727 | 0.80 | POLB (0.36) | MAPTHSD17B10TDP1MEN1KMT2A | |
| SCHEMBL326813 | 0.80 | TDP1 (0.63) | TDP1CYP11B1CYP11B2TNFSMN1; SMN2 | |
| SCHEMBL6128998 | 0.79 | POLB (0.43) | MAPTHSD17B10NPC1RAB9AMEN1 | |
| Bromide SCHEMBL11005339 | 0.78 | TDP1 (0.61) | TDP1CYP11B1CYP11B2TNFSMN1; SMN2 | |
| SCHEMBL7643046 | 0.77 | FGFR1 (0.50) | MAPTHSD17B10TDP1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0088595-B1 | CYANINE DYES FOR SENSITIZING SILVER HALIDE EMULSIONS TO INFRARED RADIATION AND PHOTOGRAPHIC ELEMENTS INCLUDING THEM | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1986-09-24 | — | — | EP | disclosed |
| US-4515888-A | BASED ON 5-METHYL-6-METHOXYBENZOTHIAZOLE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1985-05-07 | — | — | US | disclosed |
| EP-0088595-A2 | Cyanine dyes for sensitizing silver halide emulsions to infrared radiation and photographic elements including them | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1983-09-14 | — | — | EP | disclosed |