Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23595437 | 0.89 | NAAA (0.58) | NAAAEPHX1KEAP1NFE2L2SMN1; SMN2 | |
| SCHEMBL15247178 | 0.81 | HDAC3 (0.55) | NAAAEPHX1KEAP1NFE2L2SMN1; SMN2 | |
| SCHEMBL10050310 | 0.80 | — | — | |
| Bicarbonate SCHEMBL7273907 | 0.78 | HDAC6 (0.52) | NAAAEPHX1KEAP1NFE2L2SMN1; SMN2 | |
| SCHEMBL3184451 | 0.78 | NAAA (0.66) | NAAAEPHX1KEAP1NFE2L2SMN1; SMN2 | |
| SCHEMBL5901310 | 0.77 | NAAA (0.56) | NAAAEPHX1KEAP1NFE2L2SMN1; SMN2 | |
| SCHEMBL3199790 | 0.77 | NAAA (0.56) | NAAAEPHX1KEAP1NFE2L2SMN1; SMN2 | |
| SCHEMBL9951287 | 0.77 | NAAA (0.56) | NAAAEPHX1KEAP1NFE2L2SMN1; SMN2 | |
| SCHEMBL19359643 | 0.77 | NAAA (0.56) | NAAAEPHX1KEAP1NFE2L2SMN1; SMN2 | |
| SCHEMBL14709057 | 0.76 | NAAA (0.70) | NAAAEPHX1KEAP1NFE2L2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4609673-A | ANTILIPEMIC AGENTS | BOEHRINGER MANNHEIM GMBH (DE) | 1986-09-02 | — | — | US | disclosed |