SCHEMBL10892178

SCHEMBL10892178

O=[N+]([O-])CCCNS(=O)(=O)O

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.39
TDP1 Q9NUW8 1/20 0.37
MEN1 O00255 1/20 0.33
LMNA P02545 1/20 0.33
BLM P54132 1/20 0.33
HBB P68871 1/20 0.33
KMT2A Q03164 1/20 0.33
HIF1A Q16665 1/20 0.33
CA1 P00915 2/20 0.31
CA2 P00918 2/20 0.31
GRIA1 P42261 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29229351 0.75 GRIA1 (0.42) ALDH1A1MEN1LMNAKMT2ACA1
SCHEMBL4941524 0.72
SCHEMBL918132 0.70 ALDH1A1 (0.44) ALDH1A1TDP1MEN1LMNABLM
SCHEMBL4940828 0.70
SCHEMBL5147794 0.69
SCHEMBL28412908 0.69 GRIA1 (0.37) ALDH1A1TDP1LMNACA1CA2
SCHEMBL4946659 0.68 ALDH1A1 (0.50) ALDH1A1TDP1MEN1LMNABLM
SCHEMBL4943204 0.68 ALDH1A1 (0.50) ALDH1A1TDP1MEN1LMNABLM
SCHEMBL11394257 0.67
SCHEMBL15562309 0.67 GRIA1 (0.41) ALDH1A1MEN1LMNAKMT2ACA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0126212-B1 STABILIZATION OF AQUEOUS SILICATES USING ALKALI SALTS OF SILYLORGANOSULFONATES DOW CORNING CORPORATION (US) 1986-07-02 EP disclosed
US-4503242-A CORROSION RESISTANCE, ANTIFREEZES, COOLANTS DOW CORNING CORPORATION (US) 1985-03-05 US disclosed
EP-0126212-A1 Stabilization of aqueous silicates using alkali salts of silylorganosulfonates DOW CORNING CORPORATION (US) 1984-11-28 EP disclosed