SCHEMBL4941524

SCHEMBL4941524

O=[N+]([O-])CCCNO

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4940828 0.92
SCHEMBL4943204 0.90 ALDH1A1 (0.50)
SCHEMBL4946659 0.90 ALDH1A1 (0.50)
SCHEMBL4938940 0.83
SCHEMBL29257541 0.74
SCHEMBL25233113 0.73 HIF1A (0.44)
SCHEMBL1011508 0.73
SCHEMBL719096 0.73 ALDH1A1 (0.67)
SCHEMBL10892178 0.72 ALDH1A1 (0.39)
SCHEMBL16341166 0.70 ALDH1A1 (0.72)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040110729-A1 Primary N-hydroxylamines NIH 2004-06-10 US claimed
US-6455589-B1 AN ORALLY ADMINISTRABLE EFFECTIVE UNIT SOLID DOSAGE OF A PRIMARY N-HYDROXYLAMINE OR A SALT, FREE OF NITRONE; USEFUL FOR REDUCING OXIDATIVE DAMAGE OR DELAYING SENESCENCE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2002-09-24 US claimed
US-20090124562-A1 Versipelostatin derivative, anti-cancer agent and processes for production of the derivative and agent TOUDAI TLO, LTD. (JP) 2009-05-14 US disclosed
US-20080268537-A1 PRIMARY N-HYDROXYLAMINES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2008-10-30 US disclosed
US-7285396-B1 Aβ-heme peroxidase CHILDREN'S HOSPITAL & RESEARCH CENTER AT OAKLAND (US) 2007-10-23 US disclosed
US-20070231848-A1 Abeta-heme peroxidase CHILDREN'S HOSPITAL OAKLAND RESEARCH INSTITUTE 2007-10-04 US disclosed
US-6455589-B1 AN ORALLY ADMINISTRABLE EFFECTIVE UNIT SOLID DOSAGE OF A PRIMARY N-HYDROXYLAMINE OR A SALT, FREE OF NITRONE; USEFUL FOR REDUCING OXIDATIVE DAMAGE OR DELAYING SENESCENCE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2002-09-24 US disclosed