Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10894138 | 0.88 | SMN1; SMN2 (0.46) | SMN1; SMN2BRCA1HIF1AMETAP2GAA | |
| SCHEMBL10892465 | 0.88 | SMN1; SMN2 (0.55) | SMN1; SMN2BRCA1HIF1AMETAP2GAA | |
| SCHEMBL10895441 | 0.87 | SMN1; SMN2 (0.45) | SMN1; SMN2BRCA1HIF1AMETAP2GAA | |
| Hydrochloric Acid SCHEMBL10889858 | 0.87 | SMN1; SMN2 (0.45) | SMN1; SMN2BRCA1HIF1AMETAP2GAA | |
| SCHEMBL10894742 | 0.85 | GAA (0.52) | SMN1; SMN2BRCA1HIF1AMETAP2GAA | |
| SCHEMBL10891736 | 0.85 | SMN1; SMN2 (0.47) | SMN1; SMN2BRCA1HIF1AMETAP2GAA | |
| SCHEMBL10890812 | 0.80 | GAA (0.49) | SMN1; SMN2METAP2GAAHDAC4HDAC6 | |
| SCHEMBL10894845 | 0.79 | CYP2D6 (0.47) | SMN1; SMN2BRCA1HIF1AMETAP2GAA | |
| SCHEMBL15585986 | 0.78 | SMN1; SMN2 (0.46) | SMN1; SMN2BRCA1HIF1AHDAC6BRD4 | |
| SCHEMBL10894158 | 0.78 | GAA (0.50) | SMN1; SMN2GAAHDAC4HDAC6CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4588810-A | Basic triphendioxazine dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1986-05-13 | — | — | US | disclosed |
| EP-0148390-A2 | Basic triphendioxazine dyes, their manufacture and their use | BAYER AG (DE) | 1985-07-17 | — | — | EP | disclosed |