Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | METAP2 | P50579 | 3/20 | 0.40 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.36 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.36 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10894742 | 0.90 | GAA (0.52) | SMN1; SMN2GAAMETAP2BRCA1HIF1A | |
| SCHEMBL10889054 | 0.87 | METAP2 (0.45) | GAAMETAP2ALDH1A1MAPT | |
| SCHEMBL10892465 | 0.86 | SMN1; SMN2 (0.55) | SMN1; SMN2GAAMETAP2BRCA1HIF1A | |
| SCHEMBL10892269 | 0.85 | SMN1; SMN2 (0.48) | SMN1; SMN2GAAMETAP2BRCA1HIF1A | |
| SCHEMBL10890812 | 0.84 | GAA (0.49) | SMN1; SMN2GAAMETAP2CA12CA2 | |
| SCHEMBL10894845 | 0.83 | CYP2D6 (0.47) | SMN1; SMN2GAAMETAP2BRCA1HIF1A | |
| SCHEMBL10894158 | 0.82 | GAA (0.50) | SMN1; SMN2GAACA12CA2CA9 | |
| SCHEMBL10894138 | 0.82 | SMN1; SMN2 (0.46) | SMN1; SMN2GAAMETAP2BRCA1HIF1A | |
| SCHEMBL10893997 | 0.82 | ALDH1A1 (0.40) | SMN1; SMN2GAAMETAP2BRCA1HIF1A | |
| SCHEMBL10891189 | 0.82 | GAA (0.52) | SMN1; SMN2GAACA12CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4588810-A | Basic triphendioxazine dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1986-05-13 | — | — | US | disclosed |
| EP-0148390-A2 | Basic triphendioxazine dyes, their manufacture and their use | BAYER AG (DE) | 1985-07-17 | — | — | EP | disclosed |