Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.37 |
| ▸ | BDKRB1 | P46663 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.35 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.35 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10894138 | 0.89 | SMN1; SMN2 (0.46) | SMN1; SMN2BRCA1HIF1AMETAP2KDM4E | |
| Hydrochloric Acid SCHEMBL10889858 | 0.88 | SMN1; SMN2 (0.45) | SMN1; SMN2BRCA1HIF1AMETAP2KDM4E | |
| SCHEMBL10892269 | 0.87 | SMN1; SMN2 (0.48) | SMN1; SMN2BRCA1HIF1AMETAP2KDM4E | |
| SCHEMBL10892465 | 0.83 | SMN1; SMN2 (0.55) | SMN1; SMN2BRCA1HIF1AMETAP2KDM4E | |
| SCHEMBL10894742 | 0.81 | GAA (0.52) | SMN1; SMN2BRCA1HIF1AMETAP2GAA | |
| SCHEMBL10891736 | 0.81 | SMN1; SMN2 (0.47) | SMN1; SMN2BRCA1HIF1AMETAP2KDM4E | |
| SCHEMBL10894845 | 0.78 | CYP2D6 (0.47) | SMN1; SMN2BRCA1HIF1AMETAP2KDM4E | |
| SCHEMBL10899520 | 0.77 | SMN1; SMN2 (0.37) | SMN1; SMN2BRCA1HIF1AMETAP2KDM4E | |
| SCHEMBL11017754 | 0.76 | NQO1 (0.46) | SMN1; SMN2METAP2KDM4EGAARAPGEF4 | |
| SCHEMBL10890812 | 0.76 | GAA (0.49) | SMN1; SMN2METAP2GAAALDH1A1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4588810-A | Basic triphendioxazine dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1986-05-13 | — | — | US | disclosed |