Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1189487 | 0.87 | ADRB2 (0.36) | TSHRCYP3A4ADRB2ADRB1ADRB3 | |
| SCHEMBL10356608 | 0.83 | TSHR (0.41) | TSHRCYP3A4MEN1THRBHTT | |
| SCHEMBL449530 | 0.79 | ADRB2 (0.41) | TSHRCYP3A4THRBSMN1; SMN2HPGD | |
| SCHEMBL28357448 | 0.77 | TSHR (0.43) | TSHRCYP3A4MEN1THRBHTT | |
| SCHEMBL30673 | 0.74 | TSHR (0.67) | TSHRCYP3A4MEN1THRBHTT | |
| SCHEMBL27130 | 0.74 | TSHR (0.67) | TSHRCYP3A4MEN1THRBHTT | |
| SCHEMBL1132722 | 0.74 | TSHR (0.67) | TSHRCYP3A4MEN1THRBHTT | |
| SCHEMBL8636270 | 0.74 | TSHR (0.67) | TSHRCYP3A4MEN1THRBHTT | |
| SCHEMBL217238 | 0.74 | TSHR (0.67) | TSHRCYP3A4MEN1THRBHTT | |
| SCHEMBL1133315 | 0.74 | TSHR (0.67) | TSHRCYP3A4MEN1THRBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4613451-A | SELF-CURING COATING | PPG INDUSTRIES, INC. (US) | 1986-09-23 | — | — | US | disclosed |
| US-4501872-A | FILMS; COATINGS; SELF-CURING AT LOW TEMPERATURES | PPG INDUSTRIES, INC. (US) | 1985-02-26 | — | — | US | disclosed |
| US-4467081-A | Gelable, silicate rich resins from hydrophobic polyols and volatile and/or incompatible organosilicates | PPG INDUSTRIES, INC. (US) | 1984-08-21 | — | — | US | disclosed |
| US-4446292-A | Moisture curable compositions containing reaction products of hydrophobic polyols and monomer organosilicon-containing substances | PPG INDUSTRIES, INC. (US) | 1984-05-01 | — | — | US | disclosed |