Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10892778 | 0.92 | ALDH1A1 (0.46) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL11140786 | 0.90 | HTT (0.56) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL11140228 | 0.88 | KMT2A (0.60) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL11136273 | 0.87 | HPGD (0.55) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL11146587 | 0.86 | ALDH1A1 (0.54) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL11136098 | 0.85 | MAPT (0.53) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL22695591 | 0.84 | MEN1 (0.46) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL11142510 | 0.82 | PRSS1 (0.58) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL11140471 | 0.82 | ALDH1A1 (0.52) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL10892274 | 0.82 | CA12 (0.47) | KDM4EALDH1A1HPGDHSD17B10RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4592957-A | Emulsifying a mixture of hydrophobic core and water polyamine; adding water soluble polyisocyanate bisulfite adduct | BAYER AKTIENGESELLSCHAFT (DE) | 1986-06-03 | — | — | US | disclosed |
| US-4517141-A | POLYUREAS FROM BISULFITE- MASKED POLYISOCYANATES; PROTECTIVE COLLOIDS | BAYER AKTIENGESELLSCHAFT (DE) | 1985-05-14 | — | — | US | disclosed |