Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.51 |
| ▸ | ACR | P10323 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11140786 | 0.88 | HTT (0.56) | HPGDKMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL10893735 | 0.87 | KDM4E (0.49) | HPGDMAPK1KMT2AALDH1A1NPC1 | |
| SCHEMBL11146587 | 0.87 | ALDH1A1 (0.54) | HPGDPRSS1ACRKMT2AALDH1A1 | |
| SCHEMBL532768 | 0.86 | MAPT (0.56) | HPGDPRSS1ACRKMT2AALDH1A1 | |
| SCHEMBL11315797 | 0.84 | MAPT (0.56) | HPGDMAPK1PRSS1ACRKMT2A | |
| SCHEMBL22695591 | 0.84 | MEN1 (0.46) | HPGDMAPK1PRSS1ACRKMT2A | |
| SCHEMBL10892778 | 0.83 | ALDH1A1 (0.46) | HPGDMAPK1KMT2AALDH1A1NPC1 | |
| SCHEMBL11140471 | 0.83 | ALDH1A1 (0.52) | HPGDMAPK1PRSS1ACRKMT2A | |
| SCHEMBL11136098 | 0.82 | MAPT (0.53) | HPGDKMT2AALDH1A1RAB9AMEN1 | |
| SCHEMBL14140198 | 0.82 | KMT2A (0.49) | HPGDPRSS1ACRKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4392999-A | COLORFAST BROWN, RED AND ORANGE | CIBA-GEIGY CORPORATION (US) | 1983-07-12 | — | — | US | disclosed |
| US-4263205-A | FOR COLORING POLYMERS, LACQUERS | CIBA-GEIGY CORPORATION (US) | 1981-04-21 | — | — | US | disclosed |
| US-4229344-A | Monazo pigments containing hydroxynaphthoylaminobenzimidazalone radical | CIBA-GEIGY CORPORATION (US) | 1980-10-21 | — | — | US | disclosed |