Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
| ▸ | CETP | P11597 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TAS2R14 | Q9NYV8 | 4/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11681964 | 0.89 | CETP (0.48) | ESR1CETPMEN1THRBAPEX1 | |
| SCHEMBL11682424 | 0.85 | MTNR1A (0.47) | ESR1MTNR1AMTNR1BTAS2R14PGR | |
| SCHEMBL11684276 | 0.85 | MAPT (0.43) | MEN1THRBAPEX1RECQLBLM | |
| SCHEMBL735955 | 0.84 | TSHR (0.58) | MEN1THRBAPEX1RECQLBLM | |
| SCHEMBL8517200 | 0.84 | CNR2 (0.50) | CETPMEN1THRBAPEX1RECQL | |
| SCHEMBL11685704 | 0.84 | S1PR1 (0.50) | CETPMEN1THRBAPEX1RECQL | |
| SCHEMBL29429236 | 0.84 | CNR2 (0.50) | CETPMEN1THRBAPEX1RECQL | |
| SCHEMBL11682389 | 0.82 | KMT2A (0.47) | MEN1THRBAPEX1RECQLBLM | |
| SCHEMBL5351677 | 0.82 | MEN1 (0.58) | MEN1THRBAPEX1RECQLBLM | |
| SCHEMBL7888440 | 0.82 | TSHR (0.58) | MEN1THRBAPEX1RECQLBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4582897-A | 2-AZO-4-SULFO-4-METHYLDIPHENYL SULFONE DERIVATIVES | CIBA-GEIGY CORPORATION (US) | 1986-04-15 | — | — | US | disclosed |
| EP-0042357-B1 | AZO DYES, THEIR PREPARATION AND USE | CIBA-GEIGY AG (CH) | 1984-06-06 | — | — | EP | disclosed |
| EP-0042357-A2 | Azo dyes, their preparation and use | CIBA-GEIGY AG (CH) | 1981-12-23 | — | — | EP | disclosed |
| US-4180503-A | FOR DYEING POLYAMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-12-25 | — | — | US | disclosed |
| US-4124581-A | FOR NATURAL AND SYNTHETIC FIBERS, COLORFAST | BAYER AKTIENGESELLSCHAFT (DE) | 1978-11-07 | — | — | US | disclosed |
| US-4041024-A | FOR POLYAMIDES AND POLYURETHANES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-08-09 | — | — | US | disclosed |