Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11685293 | 0.90 | KMT2A (0.44) | LMNADRD2DRD3CNR1CNR2 | |
| SCHEMBL11682403 | 0.89 | LMNA (0.41) | MAPTKDM4ELMNAUSP2CNR2 | |
| SCHEMBL11683255 | 0.87 | USP2 (0.47) | MAPTKDM4ELMNAUSP2TAS2R14 | |
| SCHEMBL11680597 | 0.85 | MEN1 (0.41) | MAPTLMNACNR2MEN1THRB | |
| SCHEMBL10894436 | 0.85 | ESR1 (0.49) | KDM4ECNR1CNR2TAS2R14PGR | |
| SCHEMBL11681443 | 0.84 | KMT2A (0.39) | MAPTKDM4ELMNADRD2DRD3 | |
| SCHEMBL11682360 | 0.83 | CNR2 (0.45) | MAPTKDM4ELMNACNR2MEN1 | |
| SCHEMBL11683398 | 0.82 | LMNA (0.43) | MAPTKDM4ELMNAMEN1THRB | |
| SCHEMBL11684683 | 0.80 | TSHR (0.51) | MAPTKDM4ECNR1CNR2MEN1 | |
| SCHEMBL11682723 | 0.80 | CNR2 (0.42) | MAPTDRD2DRD3CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4041024-A | FOR POLYAMIDES AND POLYURETHANES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-08-09 | — | — | US | disclosed |