Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.45 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 3/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | STK10 | O94804 | 1/20 | 0.40 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28688587 | 0.78 | EPHX1 (0.52) | CA2LMNAMAPTEPHX2EPHX1 | |
| SCHEMBL11942144 | 0.77 | CA2 (0.52) | TSHRHSD17B10CA2CA1HSD17B3 | |
| SCHEMBL10001895 | 0.77 | HSD17B10 (0.50) | TSHRHSD17B10CA2CA1HSD17B3 | |
| SCHEMBL18427395 | 0.76 | TSHR (0.48) | TSHRHSD17B10CA2CA1HSD17B3 | |
| Hydrochloric Acid SCHEMBL4206989 | 0.76 | CA2 (0.50) | TSHRHSD17B10CA2CA1HSD17B3 | |
| SCHEMBL14817944 | 0.74 | TSHR (0.46) | TSHRHSD17B10CA2CA1HSD17B3 | |
| SCHEMBL1487927 | 0.73 | TNIK (0.41) | HSD17B10HSD17B2LMNAESR2GRM4 | |
| SCHEMBL6991764 | 0.72 | ALDH1A1 (0.47) | TSHRHSD17B10CA2CA1HSD17B3 | |
| SCHEMBL11309079 | 0.72 | TSHR (0.53) | TSHRHSD17B10ALDH1A1LMNAMAPT | |
| SCHEMBL14279552 | 0.72 | NR1H4 (0.51) | TSHRHSD17B10CA2CA1HSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4565655-A | Diazabicyclononene antibacterials | ELI LILLY AND COMPANY (US) | 1986-01-21 | — | — | US | disclosed |