SCHEMBL1089533

SCHEMBL1089533

CCCC(=O)OC1CC2C=CC1C2

nearest known ligand 0.43

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 4/20 0.36
ALDH1A1 P00352 1/20 0.36
SLC18A3 Q16572 1/20 0.36
KDM4E B2RXH2 2/20 0.35
LMNA P02545 1/20 0.35
NLRP3 Q96P20 1/20 0.33
NAAA Q02083 1/20 0.33
PRKCA P17252 5/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2961193 0.90 NAAA (0.41) EPHX2NAAAPRKCA
SCHEMBL7062726 0.89 NAAA (0.46) EPHX2LMNANAAAPRKCA
SCHEMBL1087620 0.86 EPHX2 (0.41) EPHX2ALDH1A1KDM4ELMNA
SCHEMBL2070936 0.85 EPHX2 (0.37) EPHX2ALDH1A1KDM4ELMNA
SCHEMBL32688488 0.83 EPHX2 (0.36) EPHX2ALDH1A1KDM4ELMNA
SCHEMBL32689094 0.80 EPHX2 (0.40) EPHX2ALDH1A1KDM4ELMNA
SCHEMBL28733937 0.79 KDM4E (0.38) EPHX2ALDH1A1KDM4ELMNA
SCHEMBL5352666 0.78 KDM4E (0.33) EPHX2ALDH1A1KDM4ELMNA
SCHEMBL32688978 0.78 EPHX2 (0.35) EPHX2ALDH1A1KDM4ELMNA
SCHEMBL301572 0.77 KDM4E (0.40) EPHX2ALDH1A1KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250313523-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NORBORNANE AND NORBORNENE DERIVATIVES OSMO LABS, PBC 2025-10-09 US disclosed
US-8535872-B2 Thermally cured underlayer for lithographic application FUJIFILM ELECTRONIC MATERIALS, U.S.A., INC. (US) 2013-09-17 US disclosed
US-20120178871-A1 THERMALLY CURED UNDERLAYER FOR LITHOGRAPHIC APPLICATION DE BINOD B (US) 2012-07-12 US disclosed
US-8153346-B2 Hydroxyl containing polymer, amino crosslinking agent and thermal acid generator; undercoating for multilayer lithography material FUJIFILM ELECTRONIC MATERIALS, U.S.A., INC. (US) 2012-04-10 US disclosed
US-7754832-B2 Block copolyolefins possessing a tapered structure THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-07-13 US disclosed
US-7727705-B2 High etch resistant underlayer compositions for multilayer lithographic processes FUJIFILM ELECTRONIC MATERIALS, U.S.A., INC. (US) 2010-06-01 US disclosed
WO-2008140846-A1 HIGH ETCH RESISTANT UNDERLAYER COMPOSITIONS FOR MULTILAYER LITHOGRAPHIC PROCESSES FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2008-11-20 WO disclosed
WO-2008103776-A2 THERMALLY CURED UNDERLAYER FOR LITHOGRAPHIC APPLICATION FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2008-08-28 WO disclosed
US-20080206667-A1 HIGH ETCH RESISTANT UNDERLAYER COMPOSITIONS FOR MULTILAYER LITHOGRAPHIC PROCESSES FUJIFILM ELECTRONIC MATERIALS, U.S.A., INC. 2008-08-28 US disclosed
US-20080206676-A1 THERMALLY CURED UNDERLAYER FOR LITHOGRAPHIC APPLICATION FUJIFILM ELECTRONIC MATERIALS, U.S.A, INC 2008-08-28 US disclosed
WO-2007055772-A2 BLOCK COPOLYOLEFINS POSSESSING A TAPERED STRUCTURE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2007-05-18 WO disclosed
US-20060094827-A1 Block copolyolefins possessing a tapered structure REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE 2006-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250313523-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NORBORNANE AND NORBORNENE DERIVATIVES CYP8B1, CYP1B1, BBOX1 EPHX2 575/4885ALDH1A1 117/4885SLC18A3 4002/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.