Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.41 |
| ▸ | F9 | P00740 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3372786 | 0.87 | MAOB (0.46) | MAOBNTRK1NTRK2F9PDE10A | |
| SCHEMBL3423976 | 0.86 | MAOB (0.46) | MAOBNTRK1NTRK2F9PDE10A | |
| Lithium Ion SCHEMBL3423977 | 0.85 | MAOB (0.45) | MAOBNTRK1NTRK2F9PDE10A | |
| SCHEMBL10896019 | 0.82 | IDO1 (0.42) | MAOBNTRK1NTRK2F9PDE10A | |
| SCHEMBL4556153 | 0.81 | TDP1 (0.47) | MAOBNTRK1NTRK2F9PDE10A | |
| SCHEMBL16176685 | 0.78 | CACNA1H (0.51) | NTRK1NTRK2F9CACNA1GCACNA1B | |
| SCHEMBL9597974 | 0.78 | PDE10A (0.47) | MAOBNTRK1NTRK2F9PDE10A | |
| SCHEMBL9570340 | 0.78 | PDE10A (0.47) | MAOBNTRK1NTRK2F9PDE10A | |
| SCHEMBL10284701 | 0.78 | DDAH1 (0.53) | PDE10ACACNA1HIDO1KDM4EALDH1A1 | |
| SCHEMBL367831 | 0.78 | IDO1 (0.45) | NTRK1NTRK2PDE10ACACNA1GCACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4612049-A | BENZOTHI ZOLYL THIO-, BENZIMIDAZOLYLTHIO- OR BENZOXAZOLYLTHIO-SUBSTITUTED CARBOXY ACID | CIBA-GEIGY CORPORATION (US) | 1986-09-16 | — | — | US | disclosed |