Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL146110 | 0.97 | TSHR (0.53) | TSHRACHEALDH1A1CA1CA2 | |
| Fluoride Ion SCHEMBL9296021 | 0.94 | TSHR (0.50) | TSHRACHEALDH1A1CA1CA2 | |
| Hydrochloric Acid SCHEMBL3843197 | 0.94 | TSHR (0.50) | TSHRACHEALDH1A1CA1CA2 | |
| SCHEMBL29464989 | 0.87 | TSHR (0.43) | TSHRACHEALDH1A1CA1CA2 | |
| SCHEMBL4139925 | 0.87 | ACHE (0.46) | TSHRACHEALDH1A1CA1CA2 | |
| SCHEMBL5160180 | 0.81 | TSHR (0.43) | TSHRACHEALDH1A1CA1CA2 | |
| Acetic Acid SCHEMBL10895782 | 0.81 | HPGD (0.41) | TSHRACHEALDH1A1CA1TDP1 | |
| SCHEMBL28442464 | 0.79 | ACHE (0.36) | TSHRACHEALDH1A1CA1CA2 | |
| SCHEMBL5583966 | 0.79 | TSHR (0.41) | TSHRACHEALDH1A1CA1CA2 | |
| SCHEMBL29409822 | 0.79 | TSHR (0.41) | TSHRACHEALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4594445-A | Producing ester or secondary amide | EASTMAN KODAK COMPANY (US) | 1986-06-10 | — | — | US | disclosed |
| EP-0165168-A2 | Carbonylation process for the production of aromatic acids and derivatives thereof | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1985-12-18 | — | — | EP | disclosed |