Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 5/20 | 0.62 |
| ▸ | TOP1 | P11387 | 4/20 | 0.51 |
| ▸ | CYCS | P99999 | 4/20 | 0.49 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | STAT1 | P42224 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10751331 | 0.99 | TERT (0.63) | TERTTOP1CYCSENPP2ABCG2 | |
| Bromide SCHEMBL10896967 | 0.91 | TERT (0.57) | TERTTOP1CYCSENPP2ABCG2 | |
| Hydrochloric Acid SCHEMBL19718144 | 0.91 | TERT (0.59) | TERTTOP1CYCSENPP2ABCG2 | |
| SCHEMBL10724808 | 0.90 | TERT (0.58) | TERTTOP1CYCSENPP2ABCG2 | |
| Bromide SCHEMBL10894063 | 0.88 | TERT (0.65) | TERTTOP1CYCSENPP2ABCG2 | |
| SCHEMBL10726817 | 0.88 | TERT (0.61) | TERTTOP1CYCSENPP2ABCG2 | |
| Bromide SCHEMBL10730446 | 0.87 | TERT (0.64) | TERTTOP1CYCSENPP2ABCG2 | |
| SCHEMBL10724268 | 0.87 | TERT (0.67) | TERTTOP1CYCSENPP2ABCG2 | |
| Iodide SCHEMBL10896392 | 0.87 | TERT (0.60) | TERTTOP1CYCSENPP2ABCG2 | |
| Bromide SCHEMBL19718098 | 0.82 | TERT (0.55) | TERTTOP1CYCSENPP2ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4614723-A | Porphyrin derivatives as fluorescent markers for immunoassays | HOFFMANN-LA ROCHE INC. (US) | 1986-09-30 | — | — | US | disclosed |