Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 6/20 | 0.65 |
| ▸ | TOP1 | P11387 | 4/20 | 0.50 |
| ▸ | CYCS | P99999 | 4/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL10730446 | 0.99 | TERT (0.64) | TERTTOP1CYCSABCG2ENPP2 | |
| SCHEMBL10724268 | 0.99 | TERT (0.67) | TERTTOP1CYCSABCG2ENPP2 | |
| Bromide SCHEMBL10724907 | 0.90 | TERT (0.58) | TERTTOP1CYCSABCG2ENPP2 | |
| SCHEMBL10729176 | 0.90 | TERT (0.61) | TERTTOP1CYCSABCG2ENPP2 | |
| Bromide SCHEMBL10896267 | 0.88 | TERT (0.62) | TERTTOP1CYCSABCG2ENPP2 | |
| SCHEMBL10724093 | 0.88 | TERT (0.68) | TERTTOP1CYCSABCG2ENPP2 | |
| SCHEMBL10751331 | 0.87 | TERT (0.63) | TERTTOP1CYCSABCG2ENPP2 | |
| Iodide SCHEMBL10724109 | 0.87 | TERT (0.67) | TERTTOP1CYCSABCG2ENPP2 | |
| Tmpyp4 SCHEMBL265519 | 0.82 | TERT (0.97) | TERTTOP1CYCSABCG2ENPP2 | |
| Tmpyp4 SCHEMBL29369473 | 0.80 | TERT (1.00) | TERTTOP1CYCSABCG2ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4614723-A | Porphyrin derivatives as fluorescent markers for immunoassays | HOFFMANN-LA ROCHE INC. (US) | 1986-09-30 | — | — | US | disclosed |