Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL383436 | 0.90 | SMN1; SMN2 (0.50) | SMN1; SMN2KMT2AKDM4EATMMAPT | |
| SCHEMBL28418543 | 0.90 | SMN1; SMN2 (0.50) | SMN1; SMN2KMT2AKDM4EATMMAPT | |
| SCHEMBL13332956 | 0.90 | SMN1; SMN2 (0.50) | SMN1; SMN2KMT2AKDM4EATMMAPT | |
| Cyclopropanecarboxylic Acid Amide SCHEMBL5661 | 0.90 | — | — | |
| SCHEMBL9797557 | 0.90 | SMN1; SMN2 (0.50) | SMN1; SMN2KMT2AKDM4EATMMAPT | |
| Cyclopropanecarboxylic Acid Amide SCHEMBL6927157 | 0.90 | SMN1; SMN2 (0.50) | SMN1; SMN2KMT2AKDM4EATMMAPT | |
| Cyclopropanecarboxylic Acid Amide SCHEMBL435434 | 0.87 | — | — | |
| Cyclopropanecarboxylic Acid Amide SCHEMBL11534774 | 0.87 | — | — | |
| Cyclopropanecarboxylic Acid Amide SCHEMBL29193681 | 0.87 | — | — | |
| Cyclopropanecarboxylic Acid Amide SCHEMBL4079465 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007092681-A2 | PIPERIDINYL DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-08-16 | — | — | WO | disclosed |
| US-4605521-A | USIN& A DEHYDRATION AGENT AND QUATERNARY AMMONIUM SALT CATALYST | EASTMAN KODAK COMPANY (US) | 1986-08-12 | — | — | US | disclosed |
| US-4056544-A | Anthraquinone compounds | BAYER AKTIENGESELLSCHAFT (DT) | 1977-11-01 | — | — | US | disclosed |