Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10889389 | 0.81 | ESR1 (0.37) | KDM4E | |
| SCHEMBL10891573 | 0.78 | ALDH1A1 (0.33) | EPHX2KDM4E | |
| SCHEMBL10890595 | 0.71 | ALDH1A1 (0.40) | KDM4E | |
| SCHEMBL10897185 | 0.71 | CRHR1 (0.33) | KDM4ECRHR1 | |
| SCHEMBL11579537 | 0.69 | SMN1; SMN2 (0.35) | — | |
| SCHEMBL29229529 | 0.66 | CA12 (0.39) | KDM4ETDP1 | |
| SCHEMBL13928564 | 0.63 | NPC1 (0.39) | EPHX2KDM4ETDP1 | |
| SCHEMBL9116589 | 0.63 | — | — | |
| SCHEMBL9313063 | 0.63 | — | — | |
| SCHEMBL8106157 | 0.60 | NPC1 (0.43) | KDM4ETDP1CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4612395-A | Process for the production of N-(2-methyl-4-chlorophenyl)-formamidine derivatives | CIBA-GEIGY CORPORATION (US) | 1986-09-16 | — | — | US | disclosed |