SCHEMBL108972

SCHEMBL108972

C[C@](O)(CBr)C(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2189780 1.00
SCHEMBL5378617 1.00
SCHEMBL28277821 0.97
SCHEMBL6054231 0.78 ALDH1A1 (0.56)
SCHEMBL30678921 0.77
SCHEMBL3633544 0.77
SCHEMBL6054302 0.75 ALDH1A1 (0.53)
SCHEMBL12332441 0.74
SCHEMBL17481688 0.74
SCHEMBL14682064 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 493 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110156584-B Synthesis method of (2R) -3-bromo-2-hydroxy-2-methylpropanoic acid 长春金赛药业有限责任公司 2023-04-07 CN claimed
CN-108531188-B Water-based drilling fluid drill cutting treating agent and preparation method thereof 中国石油天然气集团有限公司 2020-09-04 CN claimed
CN-111138353-A Nicotinate hydrate and preparation method thereof 宁波耆健医药科技有限公司 2020-05-12 CN claimed
CN-110981794-A Synthetic method of nicotinate 宁波耆健医药科技有限公司 2020-04-10 CN claimed
CN-101863806-B Preparation method of medicine (R)-Bicalutamide for resisting prostatic cancer HEBEI PROVINCE PHARMACEUTICAL INDUSTRY RES INST CO LTD 2013-02-13 CN claimed
CN-101863806-A Preparation method of medicine (R)-Bicalutamide for resisting prostatic cancer HEBEI PROVINCE PHARMACEUTICAL INDUSTRY RES INST CO LTD 2010-10-20 CN claimed
US-20260008758-A1 LINEAR DIPEPTIDYL PEPTIDASE 1 INHIBITORS AND USES THEREOF INSMED INCORPORATED 2026-01-08 US disclosed
US-12398121-B2 Anti-cancer nuclear hormone receptor-targeting compounds NUVATION BIO INC. (US) 2025-08-26 US disclosed
WO-2025102293-A1 NEUROACTIVE ANDROGEN RECEPTOR MODULATOR AND USE THEREOF 北京脑科学与类脑研究所 2025-05-22 WO disclosed
US-12215086-B2 Selective androgen receptor degrader (SARD) ligands and methods of use thereof UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2025-02-04 US disclosed
US-12208141-B2 Anti-cancer nuclear hormone receptor-targeting compounds NUVATION BIO INC. (US) 2025-01-28 US disclosed
US-12202815-B2 Selective androgen receptor degrader (SARD) ligands and methods of use thereof UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2025-01-21 US disclosed
US-12128026-B2 Selective androgen receptor degrader (SARD) ligands and methods of use thereof UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2024-10-29 US disclosed
US-20030232792-A1 Selective androgen receptor modulators and methods of use thereof TENNESSEE RESEARCH CORPORATION, THE UNIVERSITY OF 2003-12-18 US disclosed
US-20030225040-A1 Selective androgen receptor modulators and methods of use thereof UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2003-12-04 US disclosed
US-6569896-B2 Useful for oral testosterone replacement therapy, male contraception, maintaining sexual desire in women, treating prostate cancer and imaging prostate cancer THE UNIVERSITY OF TENNESSEE RESEARCH CORPORATION 2003-05-27 US disclosed
US-20020099096-A1 Selective androgen receptor modulators and methods of use thereof UNIVERSITY OF TENNESSEE RESEARCH CORPORATION, THE 2002-07-25 US disclosed
WO-2002016310-A1 SELECTIVE ANDROGEN RECEPTOR MODULATORS AND METHODS OF USE THEREOF THE UNIVERSITY OF TENNESSEE RESEARCH CORPORATION (US) 2002-02-28 WO disclosed
US-4633025-A INTERMEDIATES FOR SYNTHESIS OF PG ANALOGS MILES LABORATORIES, INC. (US) 1986-12-30 US disclosed
EP-0198352-A2 Method for preparing (+)R-2-methyl-hexane-1,2-diol MILES INC. (US) 1986-10-22 EP disclosed