SCHEMBL2189780

SCHEMBL2189780

CC(O)(CBr)C(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL108972 1.00
SCHEMBL5378617 1.00
SCHEMBL28277821 0.97
SCHEMBL6054231 0.78 ALDH1A1 (0.56)
SCHEMBL30678921 0.77
SCHEMBL3633544 0.77
SCHEMBL6054302 0.75 ALDH1A1 (0.53)
SCHEMBL12332441 0.74
SCHEMBL17481688 0.74
SCHEMBL14682064 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 231 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108531188-B Water-based drilling fluid drill cutting treating agent and preparation method thereof 中国石油天然气集团有限公司 2020-09-04 CN claimed
CN-111138353-A Nicotinate hydrate and preparation method thereof 宁波耆健医药科技有限公司 2020-05-12 CN claimed
CN-110981794-A Synthetic method of nicotinate 宁波耆健医药科技有限公司 2020-04-10 CN claimed
CN-110156584-A The synthetic method of one kind bromo- 2- hydroxy-2-methyl propionic acid of (2R) -3- 宁波耆健医药科技有限公司 2019-08-23 CN claimed
CN-109761778-A A kind of method of synthesizing optical active alpha-hydroxypropanamide derivative 石家庄市度智医药科技有限公司 2019-05-17 CN claimed
CN-108531188-A A kind of inorganic agent and preparation method thereof of water-base drilling fluid drilling cuttings 中国石油天然气集团有限公司 2018-09-14 CN claimed
CN-101863806-B Preparation method of medicine (R)-Bicalutamide for resisting prostatic cancer HEBEI PROVINCE PHARMACEUTICAL INDUSTRY RES INST CO LTD 2013-02-13 CN claimed
CN-101863806-A Preparation method of medicine (R)-Bicalutamide for resisting prostatic cancer HEBEI PROVINCE PHARMACEUTICAL INDUSTRY RES INST CO LTD 2010-10-20 CN claimed
US-12398121-B2 Anti-cancer nuclear hormone receptor-targeting compounds NUVATION BIO INC. (US) 2025-08-26 US disclosed
US-12215086-B2 Selective androgen receptor degrader (SARD) ligands and methods of use thereof UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2025-02-04 US disclosed
US-12208141-B2 Anti-cancer nuclear hormone receptor-targeting compounds NUVATION BIO INC. (US) 2025-01-28 US disclosed
US-12202815-B2 Selective androgen receptor degrader (SARD) ligands and methods of use thereof UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2025-01-21 US disclosed
US-12128026-B2 Selective androgen receptor degrader (SARD) ligands and methods of use thereof UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2024-10-29 US disclosed
US-12115146-B2 Treatment of skeletal-related events for breast cancer patients UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2024-10-15 US disclosed
EP-1546093-A1 PROCESS FOR MAKING BICALUTAMIDE AND INTERMEDIATES THEREOF Synthon B.V. (NL) 2005-06-29 EP disclosed
US-6818766-B2 USING P-FLUOROBENZENESULFINIC ACID SYNTHON BV (NL) 2004-11-16 US disclosed
WO-2004031136-A1 PROCESS FOR MAKING BICALUTAMIDE AND INTERMEDIATES THEREOF SYNTHON B.V. (NL) 2004-04-15 WO disclosed
US-20040068135-A1 Process for making bicalutamide and intermediates thereof SYNTHON IP INC. 2004-04-08 US disclosed
CN-1471508-A Selective androgen receptor modulators and methods of use thereof ��ѧ�о��� 2004-01-28 CN disclosed
US-20030073742-A1 Process for making bicalutamide and intermediates thereof SYNTHON B.V. (NL) 2003-04-17 US disclosed