Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.36 |
| ▸ | APAF1 | O14727 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.36 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.36 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11039232 | 0.89 | TDP1 (0.47) | CTDSP1TDP1APAF1TSHRLMNA | |
| SCHEMBL10646020 | 0.89 | KCNH2 (0.50) | KCNH2CTDSP1TDP1APAF1TSHR | |
| SCHEMBL10646029 | 0.89 | KCNH2 (0.50) | KCNH2CTDSP1TDP1APAF1TSHR | |
| SCHEMBL11039229 | 0.89 | TDP1 (0.47) | CTDSP1TDP1APAF1TSHRLMNA | |
| SCHEMBL10643010 | 0.89 | TDP1 (0.43) | KCNH2CTDSP1TDP1APAF1TSHR | |
| SCHEMBL10643005 | 0.89 | TDP1 (0.43) | KCNH2CTDSP1TDP1APAF1TSHR | |
| SCHEMBL10644366 | 0.89 | TDP1 (0.40) | KCNH2CTDSP1TDP1APAF1TSHR | |
| SCHEMBL10644360 | 0.89 | TDP1 (0.40) | KCNH2CTDSP1TDP1APAF1TSHR | |
| SCHEMBL11055001 | 0.87 | ABCC4 (0.48) | KCNH2CTDSP1TDP1TSHRL3MBTL1 | |
| SCHEMBL11055004 | 0.87 | ABCC4 (0.48) | KCNH2CTDSP1TDP1TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0191507-A2 | New 2-oxyimino-3-oxobutyric acid derivatives and process for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-08-20 | — | — | EP | disclosed |