Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC4 | O15439 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SPOP | O43791 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11055001 | 1.00 | ABCC4 (0.48) | ABCC4PDE4AHSD17B10TDP1ALDH1A1 | |
| SCHEMBL10643585 | 0.90 | TDP1 (0.56) | ABCC4PDE4AHSD17B10TDP1ALDH1A1 | |
| SCHEMBL10643588 | 0.90 | TDP1 (0.56) | ABCC4PDE4AHSD17B10TDP1ALDH1A1 | |
| SCHEMBL10644360 | 0.87 | TDP1 (0.40) | ABCC4PDE4AHSD17B10TDP1ALDH1A1 | |
| SCHEMBL10644366 | 0.87 | TDP1 (0.40) | ABCC4PDE4AHSD17B10TDP1ALDH1A1 | |
| SCHEMBL10897232 | 0.87 | KCNH2 (0.39) | ABCC4PDE4AHSD17B10TDP1ALDH1A1 | |
| SCHEMBL10646029 | 0.87 | KCNH2 (0.50) | ABCC4PDE4AHSD17B10TDP1ALDH1A1 | |
| SCHEMBL10646020 | 0.87 | KCNH2 (0.50) | ABCC4PDE4AHSD17B10TDP1ALDH1A1 | |
| SCHEMBL10646054 | 0.85 | TDP1 (0.53) | ABCC4HSD17B10TDP1ALDH1A1NR1I2 | |
| SCHEMBL10646060 | 0.85 | TDP1 (0.53) | ABCC4HSD17B10TDP1ALDH1A1NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4452851-A | BACTERICIDES, ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-06-05 | — | — | US | disclosed |