Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10897403 | 1.00 | MAOA (0.47) | MAOAMAOBTRPV1SIGMAR1L3MBTL1 | |
| SCHEMBL10889939 | 0.98 | TRPV1 (0.48) | MAOAMAOBTRPV1SIGMAR1 | |
| SCHEMBL10895606 | 0.98 | TRPV1 (0.48) | MAOAMAOBTRPV1SIGMAR1 | |
| SCHEMBL10889936 | 0.98 | TRPV1 (0.48) | MAOAMAOBTRPV1SIGMAR1 | |
| SCHEMBL10895596 | 0.98 | TRPV1 (0.48) | MAOAMAOBTRPV1SIGMAR1 | |
| SCHEMBL11006778 | 0.86 | TRPV1 (0.48) | MAOAMAOBTRPV1SIGMAR1 | |
| SCHEMBL97474 | 0.85 | GPR52 (0.48) | MAOB | |
| SCHEMBL97473 | 0.85 | GPR52 (0.48) | MAOB | |
| SCHEMBL28645454 | 0.82 | MAOB (0.62) | MAOAMAOBTRPV1SIGMAR1L3MBTL1 | |
| SCHEMBL1045005 | 0.80 | TRPV1 (0.49) | MAOAMAOBTRPV1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4605645-A | ANTITUMOR AGENTS | TEIJIN LIMITED (JP) | 1986-08-12 | — | — | US | disclosed |
| EP-0081386-B1 | 5-FLUORO-2'-DEOXYURIDINE DERIVATIVES AND A PROCESS FOR THE PREPARATION THEREOF | TEIJIN LIMITED (JP) | 1985-05-29 | — | — | EP | disclosed |
| EP-0081386-A1 | 5-Fluoro-2'-deoxyuridine derivatives and a process for the preparation thereof | TEIJIN LIMITED (JP) | 1983-06-15 | — | — | EP | disclosed |