SCHEMBL10897900

SCHEMBL10897900

Cn1c(-c2ccccc2)c(N)c(=O)n1-c1ccc(S(=O)(=O)O)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 5/20 0.48
BCHE P06276 1/20 0.48
PTGS1 P23219 3/20 0.41
NPC1 O15118 1/20 0.40
HTT P42858 1/20 0.40
ALDH1A1 P00352 2/20 0.39
CYP2C19 P33261 1/20 0.39
TSHR P16473 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
ALOX15 P16050 2/20 0.38
LMNA P02545 2/20 0.38
KDM4E B2RXH2 1/20 0.38
MAPT P10636 1/20 0.38
ALOX12 P18054 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
DPP4 P27487 1/20 0.38
ADORA3 P0DMS8 1/20 0.38
EIF2AK3 Q9NZJ5 1/20 0.37
EIF2AK4 Q9P2K8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3698266 0.83 BCHE (0.55) PTGS2BCHEALDH1A1TSHRSMN1; SMN2
SCHEMBL395394 0.79 BCHE (0.62) PTGS2BCHEPTGS1NPC1HTT
SCHEMBL3706181 0.77 BCHE (0.59) PTGS2BCHEALDH1A1TSHRSMN1; SMN2
Ampyrone SCHEMBL8822010 0.77 BCHE (0.68) PTGS2BCHEPTGS1ALDH1A1ALOX15
SCHEMBL3701459 0.73 BCHE (0.54) PTGS2BCHENPC1HTTALDH1A1
SCHEMBL23398382 0.72 BCHE (0.56) PTGS2BCHEPTGS1ALDH1A1TSHR
Ampyrone SCHEMBL28606780 0.72 BCHE (0.84) PTGS2BCHEPTGS1ALDH1A1TSHR
SCHEMBL11651846 0.71 CDK8 (0.45) PTGS2BCHEALDH1A1CYP2C19LMNA
SCHEMBL23402967 0.70 BCHE (0.51) PTGS2BCHENPC1HTTALDH1A1
SCHEMBL23402523 0.69 BCHE (0.51) PTGS2BCHENPC1HTTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4587100-A PEROXIDDASE ON LIGHT TRANSMISSIVE SUPPORT FUJI PHOTO FILM CO., LTD. (JP) 1986-05-06 US disclosed
EP-0103288-A1 Multilayer analytical element FUJI PHOTO FILM CO., LTD. (JP) 1984-03-21 EP disclosed
EP-0101945-A1 Multilayer analytical element FUJI PHOTO FILM CO., LTD. (JP) 1984-03-07 EP disclosed