SCHEMBL23398382

SCHEMBL23398382

Cn1c(=O)c(N)c(-c2ccccc2)n1-c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.56
PTGS2 P35354 1/20 0.56
ALOX15 P16050 3/20 0.44
ALDH1A1 P00352 2/20 0.44
LMNA P02545 2/20 0.42
ADORA3 P0DMS8 1/20 0.42
NAPRT Q6XQN6 2/20 0.42
TSHR P16473 3/20 0.41
CYP1A2 P05177 2/20 0.41
THRB P10828 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CDK8 P49336 1/20 0.41
ACVR1 Q04771 1/20 0.41
KDM4E B2RXH2 3/20 0.40
GSK3A P49840 1/20 0.40
GSK3B P49841 1/20 0.40
PTGS1 P23219 1/20 0.40
PABPC1 P11940 1/20 0.40
CASP3 P42574 1/20 0.40
CASP7 P55210 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3694660 0.86 BCHE (0.65) BCHEPTGS2ALOX15ALDH1A1LMNA
SCHEMBL23402967 0.84 BCHE (0.51) BCHEPTGS2ALOX15ALDH1A1LMNA
SCHEMBL11651846 0.82 CDK8 (0.45) BCHEPTGS2ALDH1A1LMNACYP1A2
SCHEMBL943590 0.80 BCHE (0.61) BCHEPTGS2ALOX15ALDH1A1LMNA
SCHEMBL23402879 0.80 BCHE (0.45) BCHEPTGS2ALOX15ALDH1A1LMNA
SCHEMBL23402523 0.79 BCHE (0.51) BCHEPTGS2ALOX15ALDH1A1TSHR
SCHEMBL23399945 0.79 BCHE (0.44) BCHEPTGS2ALOX15ALDH1A1LMNA
SCHEMBL3698266 0.79 BCHE (0.55) BCHEPTGS2ALOX15ALDH1A1LMNA
SCHEMBL3706181 0.79 BCHE (0.59) BCHEPTGS2ALOX15ALDH1A1LMNA
SCHEMBL23401656 0.79 BCHE (0.44) BCHEPTGS2ALOX15ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3828159-A1 STORAGE AND TRANSPORT STABILIZERS FOR POLYMERIZABLE COMPOUNDS BASF SE (DE) 2021-06-02 EP disclosed