Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.68 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL395394 | 0.88 | BCHE (0.62) | BCHEPTGS2ALDH1A1ALOX15PTGS1 | |
| Ampyrone SCHEMBL28606780 | 0.87 | BCHE (0.84) | BCHEPTGS2ALDH1A1ALOX15PTGS1 | |
| Ampyrone SCHEMBL3092850 | 0.87 | BCHE (0.84) | BCHEPTGS2ALDH1A1ALOX15L3MBTL1 | |
| Ampyrone SCHEMBL27868612 | 0.84 | BCHE (0.79) | BCHEPTGS2ALDH1A1ALOX15PTGS1 | |
| Ampyrone SCHEMBL4648040 | 0.82 | BCHE (0.60) | BCHEPTGS2ALDH1A1ALOX15PTGS1 | |
| Ampyrone SCHEMBL11674586 | 0.82 | BCHE (1.00) | BCHEPTGS2ALDH1A1ALOX15MEN1 | |
| Ampyrone SCHEMBL128544 | 0.82 | BCHE (1.00) | BCHEPTGS2ALDH1A1ALOX15MEN1 | |
| Ampyrone SCHEMBL18159502 | 0.82 | BCHE (1.00) | BCHEPTGS2ALDH1A1ALOX15MEN1 | |
| Ampyrone SCHEMBL133625 | 0.82 | BCHE (0.56) | BCHEPTGS2ALDH1A1ALOX15PTGS1 | |
| Ampyrone SCHEMBL15971631 | 0.82 | BCHE (0.71) | BCHEPTGS2ALDH1A1ALOX15L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0526226-B1 | Device and method for conducting biological assays containing particulate screening system | ORTHO PHARMA CORP (US) | 1997-05-28 | — | — | EP | disclosed |
| EP-0526226-A2 | Device and method for conducting biological assays containing particulate screening system | ORTHO PHARMACEUTICAL CORPORATION (US) | 1993-02-03 | — | — | EP | disclosed |