Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.42 |
| ▸ | MAOB | P27338 | 6/20 | 0.42 |
| ▸ | ACHE | P22303 | 5/20 | 0.42 |
| ▸ | GPR183 | P32249 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10898376 | 1.00 | MAOA (0.42) | MAOAMAOBACHEGPR183KDM4E | |
| SCHEMBL10901691 | 0.90 | KCNJ1 (0.50) | MAOAMAOBACHEGPR183KDM4E | |
| SCHEMBL10901688 | 0.90 | KCNJ1 (0.50) | MAOAMAOBACHEGPR183KDM4E | |
| SCHEMBL10900963 | 0.89 | MAOA (0.45) | MAOAMAOBACHEGPR183 | |
| SCHEMBL10900958 | 0.89 | MAOA (0.45) | MAOAMAOBACHEGPR183 | |
| SCHEMBL10900320 | 0.86 | GAA (0.49) | MAOAMAOBKDM4EALDH1A1HPGD | |
| SCHEMBL10898730 | 0.85 | EBP (0.46) | MAOAMAOBACHEGPR183ALDH1A1 | |
| SCHEMBL10898734 | 0.85 | EBP (0.46) | MAOAMAOBACHEGPR183ALDH1A1 | |
| SCHEMBL10901877 | 0.82 | GPR183 (0.56) | GPR183GAAHTT | |
| SCHEMBL10901880 | 0.82 | GPR183 (0.56) | GPR183GAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4616086-A | ANTICOAGULANTS | BOEHRINGER MANNHEIM GMBH (DE) | 1986-10-07 | — | — | US | disclosed |