Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | DHCR7 | Q9UBM7 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 8/20 | 0.45 |
| ▸ | MAOB | P27338 | 8/20 | 0.45 |
| ▸ | GPR183 | P32249 | 2/20 | 0.45 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.44 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 7/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10898734 | 1.00 | EBP (0.46) | EBPSIGMAR1DHCR7MAOAMAOB | |
| SCHEMBL10900963 | 0.90 | MAOA (0.45) | MAOAMAOBGPR183GABBR2GABBR1 | |
| SCHEMBL10900958 | 0.90 | MAOA (0.45) | MAOAMAOBGPR183GABBR2GABBR1 | |
| SCHEMBL10901691 | 0.88 | KCNJ1 (0.50) | MAOAMAOBGPR183ACHEALDH1A1 | |
| SCHEMBL10901688 | 0.88 | KCNJ1 (0.50) | MAOAMAOBGPR183ACHEALDH1A1 | |
| SCHEMBL10898376 | 0.85 | MAOA (0.42) | MAOAMAOBGPR183ACHEALDH1A1 | |
| SCHEMBL10898379 | 0.85 | MAOA (0.42) | MAOAMAOBGPR183ACHEALDH1A1 | |
| SCHEMBL10901418 | 0.82 | ME2 (0.54) | GABBR2GABBR1ACHEPOLBALDH1A1 | |
| SCHEMBL10901414 | 0.82 | ME2 (0.54) | GABBR2GABBR1ACHEPOLBALDH1A1 | |
| SCHEMBL4379032 | 0.82 | GPR183 (0.51) | MAOAMAOBGPR183GABBR2GABBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4616086-A | ANTICOAGULANTS | BOEHRINGER MANNHEIM GMBH (DE) | 1986-10-07 | — | — | US | disclosed |