Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 12/20 | 0.78 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.73 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.73 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.54 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.54 |
| ▸ | GPX4 | P36969 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6796629 | 0.87 | OPRD1 (0.97) | OPRD1CYP2D6CYP19A1OPRM1MEN1 | |
| SCHEMBL1137956 | 0.86 | CYP2D6 (1.00) | OPRD1CYP2D6CYP19A1OPRM1MEN1 | |
| SCHEMBL10897567 | 0.85 | OPRD1 (0.57) | OPRD1CYP2D6CYP19A1OPRM1CHEK2 | |
| SCHEMBL10901072 | 0.83 | OPRD1 (0.79) | OPRD1CYP2D6CYP19A1OPRM1CHEK2 | |
| Norchlorcyclizine SCHEMBL2426579 | 0.83 | CYP2D6 (0.69) | OPRD1CYP2D6CYP19A1OPRM1MEN1 | |
| Norchlorcyclizine SCHEMBL467086 | 0.83 | CYP2D6 (0.86) | OPRD1CYP2D6CYP19A1OPRM1MEN1 | |
| Norchlorcyclizine SCHEMBL6556514 | 0.83 | CYP2D6 (0.86) | OPRD1CYP2D6CYP19A1OPRM1MEN1 | |
| Norchlorcyclizine SCHEMBL588655 | 0.83 | CYP2D6 (0.86) | OPRD1CYP2D6CYP19A1OPRM1MEN1 | |
| SCHEMBL10677115 | 0.82 | CHRM2 (0.70) | OPRD1CYP2D6OPRM1MEN1KMT2A | |
| Norchlorcyclizine SCHEMBL3602733 | 0.82 | CYP2D6 (0.68) | OPRD1CYP2D6CYP19A1OPRM1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4616086-A | ANTICOAGULANTS | BOEHRINGER MANNHEIM GMBH (DE) | 1986-10-07 | — | — | US | disclosed |