Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 10/20 | 0.61 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10900950 | 0.83 | OPRD1 (0.60) | OPRD1ROCK2ROCK1SLC6A4SLC6A2 | |
| Hydrochloric Acid SCHEMBL6790513 | 0.76 | OPRD1 (0.97) | OPRD1OPRM1 | |
| SCHEMBL1978575 | 0.75 | OPRD1 (0.69) | OPRD1SLC6A4SLC6A2OPRM1SLC6A3 | |
| SCHEMBL26199219 | 0.75 | OPRD1 (0.69) | OPRD1SLC6A4SLC6A2OPRM1SLC6A3 | |
| SCHEMBL8029903 | 0.75 | SLC6A4 (0.53) | SLC6A4SLC6A2KCNH2CYP2D6HTR7 | |
| SCHEMBL10901585 | 0.73 | OPRD1 (0.57) | OPRD1SLC6A4SLC6A2OPRM1SLC6A3 | |
| SCHEMBL10899180 | 0.73 | OPRD1 (0.56) | OPRD1SLC6A4SLC6A2OPRM1CYP2D6 | |
| SCHEMBL10903271 | 0.72 | OPRD1 (0.57) | OPRD1SLC6A4SLC6A2KCNH2OPRM1 | |
| SCHEMBL10901786 | 0.71 | OPRD1 (0.67) | OPRD1OPRM1RAB9A | |
| Hydrochloric Acid SCHEMBL28584197 | 0.71 | OPRD1 (0.56) | OPRD1ROCK2ROCK1SLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4616086-A | ANTICOAGULANTS | BOEHRINGER MANNHEIM GMBH (DE) | 1986-10-07 | — | — | US | disclosed |