Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 2/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10901072 | 0.83 | OPRD1 (0.79) | OPRD1OPRM1CYP2D6CYP19A1 | |
| SCHEMBL28002324 | 0.80 | SLC6A4 (0.58) | SLC6A4SLC6A2TP53ALDH1A1GLA | |
| SCHEMBL10900898 | 0.80 | OPRD1 (0.59) | OPRD1OPRM1SLC6A4SLC6A2LMNA | |
| SCHEMBL10900427 | 0.79 | OPRD1 (0.57) | OPRD1OPRM1SLC6A4SLC6A2LMNA | |
| SCHEMBL10900950 | 0.79 | OPRD1 (0.60) | OPRD1OPRM1SLC6A4SLC6A2LMNA | |
| SCHEMBL27687834 | 0.78 | SLC6A4 (0.80) | SLC6A4SLC6A2CYP2D6 | |
| SCHEMBL27363846 | 0.78 | SLC6A4 (0.80) | SLC6A4SLC6A2CYP2D6 | |
| SCHEMBL25212922 | 0.76 | RAB9A (0.52) | ALDH1A1KMT2AGAAMAPTHPGD | |
| SCHEMBL10901585 | 0.76 | OPRD1 (0.57) | OPRD1OPRM1SLC6A4SLC6A2TP53 | |
| SCHEMBL1978575 | 0.75 | OPRD1 (0.69) | OPRD1OPRM1SLC6A4SLC6A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4616086-A | ANTICOAGULANTS | BOEHRINGER MANNHEIM GMBH (DE) | 1986-10-07 | — | — | US | disclosed |