SCHEMBL10898526

SCHEMBL10898526

CCCC(C#N)C(C)C=O

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10899139 0.88 TSHR (0.42) TSHRSMN1; SMN2
SCHEMBL12181397 0.84 ADH1B (0.43) TSHRSMN1; SMN2
SCHEMBL21402024 0.83
SCHEMBL4274814 0.82
SCHEMBL12051800 0.78 TSHR (0.31) TSHRSMN1; SMN2
SCHEMBL10433057 0.77 TSHR (0.34) TSHRSMN1; SMN2
SCHEMBL280595 0.76
SCHEMBL17745024 0.75 ALOX15 (0.44) TSHR
SCHEMBL364354 0.74
SCHEMBL13467627 0.72 TSHR (0.33) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0087712-B1 METHOD FOR THE PREPARATION OF 3-CYANO-2-ALKYL ALKANALS AND USE OF 3-CYANO-2-ETHYL HEXANAL IN THE PREPARATION OF 2-PROPYLPENTANOIC ACID BASF Aktiengesellschaft (DE) 1986-05-07 EP disclosed
EP-0087712-A1 Method for the preparation of 3-cyano-2-alkyl alkanals and use of 3-cyano-2-ethyl hexanal in the preparation of 2-propylpentanoic acid BASF Aktiengesellschaft (DE) 1983-09-07 EP disclosed