SCHEMBL108987

SCHEMBL108987

CCC(=O)C(c1ccc(O)cc1)c1ccc(O)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 8/20 0.52
CYP1A2 P05177 3/20 0.52
LMNA P02545 3/20 0.52
CYP2C9 P11712 3/20 0.52
PGR P06401 2/20 0.52
CHRM2 P08172 2/20 0.52
CYP3A4 P08684 2/20 0.52
ADORA3 P0DMS8 2/20 0.52
AR P10275 2/20 0.52
CYP2D6 P10635 2/20 0.52
MAPT P10636 2/20 0.52
CHRM1 P11229 2/20 0.52
ALOX15 P16050 2/20 0.52
DRD1 P21728 2/20 0.52
TBXA2R P21731 2/20 0.52
PTGS1 P23219 2/20 0.52
SLC6A2 P23975 2/20 0.52
CYP2C19 P33261 2/20 0.52
ADRA1A P35348 2/20 0.52
OPRM1 P35372 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11579020 0.84 ESR1 (0.50) ESR1CYP1A2LMNACYP2C9PGR
SCHEMBL28256616 0.84 ALDH1A1 (0.46) CYP1A2LMNACYP2C9CYP3A4CYP2D6
SCHEMBL462447 0.82 CYP1A2 (0.66) CYP1A2LMNACHRM2CYP3A4CYP2D6
SCHEMBL17662333 0.81 ESR1 (0.47) ESR1CYP1A2LMNACYP2C9PGR
Hydrochloric Acid SCHEMBL3647675 0.80 ALDH1A1 (0.64) CYP1A2LMNACHRM2CYP3A4CYP2D6
SCHEMBL3662538 0.78 ESR1 (0.47) ESR1CYP1A2LMNACYP2C9PGR
SCHEMBL24450571 0.78 MAPT (0.45) CYP1A2MAPTSLC6A3ALDH1A1MEN1
SCHEMBL27765469 0.78 ESR1 (0.44) ESR1CYP1A2LMNACYP2C9PGR
SCHEMBL2148361 0.78 ESR1 (0.44) ESR1CYP1A2LMNACYP2C9PGR
SCHEMBL1395571 0.77 CA12 (0.55) ESR1CYP1A2LMNACYP2C9PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2424982-A1 ADAPTING MICROORGANISMS FOR AGRICULTURAL PRODUCTS De Crecy, Eudes (US) 2012-03-07 EP disclosed
WO-2010127182-A1 ADAPTING MICROORGANISMS FOR AGRICULTURAL PRODUCTS EVOLUGATE, LLC (US) 2010-11-04 WO disclosed