SCHEMBL2148361

SCHEMBL2148361

CCC(=O)C(O)C(C)c1ccc(O)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 7/20 0.44
TDP1 Q9NUW8 3/20 0.44
CYP2C9 P11712 2/20 0.44
ALOX15 P16050 2/20 0.44
LMNA P02545 1/20 0.44
CYP1A2 P05177 1/20 0.44
PGR P06401 1/20 0.44
CHRM2 P08172 1/20 0.44
CYP3A4 P08684 1/20 0.44
ADORA3 P0DMS8 1/20 0.44
AR P10275 1/20 0.44
CYP2D6 P10635 1/20 0.44
MAPT P10636 1/20 0.44
CHRM1 P11229 1/20 0.44
DRD1 P21728 1/20 0.44
TBXA2R P21731 1/20 0.44
PTGS1 P23219 1/20 0.44
SLC6A2 P23975 1/20 0.44
CYP2C19 P33261 1/20 0.44
ADRA1A P35348 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3395868 0.86 HSD17B3 (0.46) ESR1TDP1CYP2C9ALOX15LMNA
SCHEMBL108987 0.78 ESR1 (0.52) ESR1TDP1CYP2C9ALOX15LMNA
SCHEMBL11579020 0.76 ESR1 (0.50) ESR1TDP1CYP2C9ALOX15LMNA
SCHEMBL17662333 0.73 ESR1 (0.47) ESR1TDP1CYP2C9ALOX15LMNA
SCHEMBL22926766 0.73 HSD17B3 (0.47) ESR1TDP1CYP2C9ALOX15LMNA
SCHEMBL29351491 0.72 ESR1 (0.68) ESR1TDP1CYP2C9ALOX15LMNA
SCHEMBL30753092 0.72 ESR1 (0.68) ESR1TDP1CYP2C9ALOX15LMNA
SCHEMBL4247422 0.72 ESR1 (0.68) ESR1TDP1CYP2C9ALOX15LMNA
SCHEMBL11949347 0.72 ESR1 (0.68) ESR1TDP1CYP2C9ALOX15LMNA
SCHEMBL1053042 0.72 ACHE (0.53) ESR1TDP1CYP2C9ALOX15LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011081658-A2 METHODS AND COMPOSITIONS FOR PRODUCING CHEMICAL PRODUCTS FROM C. PHYTOFERMENTANTS QTEROS, INC. (US) 2011-07-07 WO disclosed