Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 2/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL263163 | 0.81 | CYP3A4 (0.58) | CYP3A4CYP2C9RECQLAKR1C3MEN1 | |
| SCHEMBL6144649 | 0.78 | CYP3A4 (0.54) | CYP3A4CYP2C9RECQLAKR1C3MEN1 | |
| SCHEMBL2138074 | 0.77 | CYP3A4 (0.62) | CYP3A4CYP2C9RECQLAKR1C3MEN1 | |
| SCHEMBL21264081 | 0.77 | CYP3A4 (0.58) | CYP3A4CYP2C9RECQLAKR1C3MEN1 | |
| SCHEMBL1716474 | 0.77 | CYP3A4 (0.58) | CYP3A4CYP2C9RECQLAKR1C3MEN1 | |
| SCHEMBL10451936 | 0.77 | CYP3A4 (0.58) | CYP3A4CYP2C9RECQLAKR1C3MEN1 | |
| SCHEMBL5014099 | 0.76 | CYP3A4 (0.56) | CYP3A4CYP2C9RECQLAKR1C3MEN1 | |
| SCHEMBL8094330 | 0.75 | CYP3A4 (0.54) | CYP3A4CYP2C9RECQLAKR1C3MEN1 | |
| SCHEMBL1716809 | 0.75 | CYP3A4 (0.54) | CYP3A4CYP2C9RECQLAKR1C3MEN1 | |
| SCHEMBL28053946 | 0.75 | CYP3A4 (0.54) | CYP3A4CYP2C9RECQLAKR1C3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0093854-B1 | HIGHLY TRANSPARENT IMPACT-RESISTANT POLYVINYL CHLORIDE-BASED MOULDING MASSES | HÜLS AKTIENGESELLSCHAFT (DE) | 1986-08-13 | — | — | EP | disclosed |
| EP-0093854-A2 | Highly transparent impact-resistant polyvinyl chloride-based moulding masses | HÜLS AKTIENGESELLSCHAFT (DE) | 1983-11-16 | — | — | EP | disclosed |