Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 3/20 | 0.40 |
| ▸ | MME | P08473 | 2/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28053946 | 1.00 | CYP3A4 (0.54) | CYP3A4CYP2C9RECQLAKR1C3AKR1C1 | |
| SCHEMBL1716809 | 1.00 | CYP3A4 (0.54) | CYP3A4CYP2C9RECQLAKR1C3AKR1C1 | |
| SCHEMBL8579738 | 0.87 | CYP3A4 (0.49) | CYP3A4CYP2C9RECQLAKR1C3AKR1C1 | |
| SCHEMBL10891535 | 0.84 | KMT2A (0.43) | CYP3A4CYP2C9LMNAMEN1KMT2A | |
| SCHEMBL30485146 | 0.83 | LMNA (0.57) | LMNAMEN1KMT2ATDP1HTT | |
| SCHEMBL196087 | 0.83 | LMNA (0.50) | CYP3A4RECQLAKR1C3LMNATDP1 | |
| SCHEMBL21264081 | 0.82 | CYP3A4 (0.58) | CYP3A4CYP2C9RECQLAKR1C3AKR1C1 | |
| SCHEMBL1716474 | 0.82 | CYP3A4 (0.58) | CYP3A4CYP2C9RECQLAKR1C3AKR1C1 | |
| SCHEMBL10451936 | 0.82 | CYP3A4 (0.58) | CYP3A4CYP2C9RECQLAKR1C3AKR1C1 | |
| SCHEMBL19717830 | 0.82 | MAPT (0.48) | CYP3A4CYP2C9RECQLLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1058537-A1 | PERSONAL HYGIENE PRODUCT WITH ENHANCED FRAGRANCE DELIVERY | Colgate-Palmolive Company (US) | 2000-12-13 | — | — | EP | disclosed |
| WO-1999044577-A1 | PERSONAL HYGIENE PRODUCT WITH ENHANCED FRAGRANCE DELIVERY | COLGATE-PALMOLIVE COMPANY (US) | 1999-09-10 | — | — | WO | disclosed |