SCHEMBL10898992

SCHEMBL10898992

CC(C)/C=C(/OCc1ccccc1)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.55
L3MBTL1 Q9Y468 2/20 0.49
TDP1 Q9NUW8 2/20 0.49
HCAR2 Q8TDS4 1/20 0.49
MAPK1 P28482 1/20 0.49
SLC6A2 P23975 1/20 0.49
SLC6A3 Q01959 1/20 0.49
KMT2A Q03164 1/20 0.49
LMNA P02545 3/20 0.46
ELANE P08246 1/20 0.45
ATM Q13315 1/20 0.44
CTSB P07858 1/20 0.44
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
MAPT P10636 1/20 0.43
HPGD P15428 1/20 0.43
POLB P06746 1/20 0.43
CA12 O43570 1/20 0.43
AKR1B10 O60218 1/20 0.43
AKR1B1 P15121 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14498309 1.00 ALDH1A1 (0.55) ALDH1A1L3MBTL1TDP1HCAR2MAPK1
SCHEMBL6063149 0.94 L3MBTL1 (0.51) ALDH1A1L3MBTL1TDP1HCAR2MAPK1
SCHEMBL6063153 0.94 L3MBTL1 (0.51) ALDH1A1L3MBTL1TDP1HCAR2MAPK1
SCHEMBL14498308 0.84 ALDH1A1 (0.60) ALDH1A1L3MBTL1TDP1HCAR2MAPK1
SCHEMBL6063156 0.82 ALDH1A1 (0.46) ALDH1A1L3MBTL1TDP1HCAR2MAPK1
SCHEMBL18652196 0.80 ALDH1A1 (0.43) ALDH1A1L3MBTL1TDP1HCAR2MAPK1
SCHEMBL2351841 0.79 ALDH1A1 (0.55) ALDH1A1L3MBTL1TDP1HCAR2MAPK1
SCHEMBL2351830 0.79 ALDH1A1 (0.55) ALDH1A1L3MBTL1TDP1HCAR2MAPK1
SCHEMBL6122148 0.79 ALDH1A1 (0.55) ALDH1A1L3MBTL1TDP1HCAR2MAPK1
SCHEMBL23630301 0.78 ALDH1A1 (0.53) ALDH1A1L3MBTL1TDP1HCAR2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0093854-B1 HIGHLY TRANSPARENT IMPACT-RESISTANT POLYVINYL CHLORIDE-BASED MOULDING MASSES HÜLS AKTIENGESELLSCHAFT (DE) 1986-08-13 EP disclosed
EP-0093855-B1 POLYMERS OF A PHENYL ALKYL ESTER OF ACRYLIC ACID, THEIR PREPARATION AND THEIR USE HÜLS AKTIENGESELLSCHAFT (DE) 1986-01-22 EP disclosed
EP-0093854-A2 Highly transparent impact-resistant polyvinyl chloride-based moulding masses HÜLS AKTIENGESELLSCHAFT (DE) 1983-11-16 EP disclosed
EP-0093855-A1 Polymers of a phenyl alkyl ester of acrylic acid, their preparation and their use HÜLS AKTIENGESELLSCHAFT (DE) 1983-11-16 EP disclosed
EP-0093856-A1 Phenyl-substituted acrylic-acid esters and their utilisation HÜLS AKTIENGESELLSCHAFT (DE) 1983-11-16 EP disclosed