Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.51 |
| ▸ | SHBG | P04278 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | STAT1 | P42224 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10901534 | 0.86 | MAOB (0.70) | MAOBHIF1ANPC1RAB9AMEN1 | |
| SCHEMBL733971 | 0.85 | MAOB (0.61) | MAOBSHBGHIF1ATYRPTGS1 | |
| SCHEMBL11713027 | 0.82 | MAOB (0.74) | MAOBSHBGNPC1RAB9AKDM4E | |
| SCHEMBL14231752 | 0.81 | MAOB (0.50) | MAOBSHBGKDM4EALDH1A1F2RL3 | |
| SCHEMBL10899406 | 0.81 | HIF1A (0.50) | MAOBSHBGHIF1ANPC1RAB9A | |
| SCHEMBL10899813 | 0.80 | APP (0.57) | MAOBNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL11711558 | 0.79 | MAOB (0.70) | MAOBSHBGNPC1RAB9AKDM4E | |
| SCHEMBL21860319 | 0.79 | MAOB (0.76) | MAOBSHBGTP53TYRPTGS1 | |
| SCHEMBL9947478 | 0.79 | MAOB (0.53) | MAOBSHBGTYRPTGS1PTGS2 | |
| SCHEMBL9947474 | 0.79 | MAOB (0.53) | MAOBSHBGTYRPTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8796306-B2 | Noxious arthropod controlling composition and heterocyclic compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-08-05 | — | — | US | disclosed |
| US-20130090353-A1 | NOXIOUS ARTHROPOD CONTROL COMPOSITION AND HETEROCYCLIC COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-04-11 | — | — | US | disclosed |
| US-4600719-A | Tetrahydropyridine and piperidine derivatives | CIBA GEIGY CORPORATION (US) | 1986-07-15 | — | — | US | disclosed |
| US-4210655-A | Anti-depressant benzofuranyl piperidines | CIBA-GEIGY CORPORATION (US) | 1980-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130090353-A1 | NOXIOUS ARTHROPOD CONTROL COMPOSITION AND HETEROCYCLIC COMPOUND | C5, C3AR1, TRPA1 | MAOB 1295/4885SHBG 4383/4885HIF1A 708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.