SCHEMBL10899485

SCHEMBL10899485

CCCCCCC(=Cc1ccccc1)CCCC

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.63
LMNA P02545 1/20 0.60
CES2 O00748 3/20 0.46
CES1 P23141 3/20 0.46
EGFR P00533 1/20 0.43
EPHX2 P34913 2/20 0.42
SOAT2 O75908 1/20 0.42
SOAT1 P35610 1/20 0.42
TUBB4A P04350 2/20 0.42
TUBB P07437 2/20 0.42
TUBA3C P0DPH7 2/20 0.42
TUBA1B P68363 2/20 0.42
TUBA4A P68366 2/20 0.42
TUBB4B P68371 2/20 0.42
TUBB3 Q13509 2/20 0.42
TUBB2A Q13885 2/20 0.42
TUBB8 Q3ZCM7 2/20 0.42
TUBA3E Q6PEY2 2/20 0.42
TUBA1A Q71U36 2/20 0.42
TUBA1C Q9BQE3 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8741682 0.98 LMNA (0.62) TDP1LMNACES2CES1EGFR
SCHEMBL28702570 0.98 TDP1 (0.65) TDP1LMNACES2CES1EGFR
SCHEMBL27498332 0.98 TDP1 (0.65) TDP1LMNACES2CES1EGFR
SCHEMBL28297913 0.98 TDP1 (0.65) TDP1LMNACES2CES1EGFR
SCHEMBL30225789 0.98 TDP1 (0.65) TDP1LMNACES2CES1EGFR
SCHEMBL30439792 0.98 TDP1 (0.65) TDP1LMNACES2CES1EGFR
SCHEMBL30439628 0.96 LMNA (0.64) TDP1LMNACES2CES1EGFR
SCHEMBL93497 0.94 LMNA (0.56) TDP1LMNACES2CES1EGFR
SCHEMBL9311704 0.91 TDP1 (0.61) TDP1LMNACES2CES1EGFR
SCHEMBL10899476 0.91 TDP1 (0.61) TDP1LMNACES2CES1EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4068676-A RELEASE AGENTS HALLIBURTON COMPANY (US) 1978-01-17 US claimed
US-4620048-A POLYMER HAVE NARROW MOLECULAR WEIGHT DISTRIBUTION EXXON RESEARCH & ENGINEERING CO. (US) 1986-10-28 US disclosed
US-4068676-A RELEASE AGENTS HALLIBURTON COMPANY (US) 1978-01-17 US disclosed