Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | CES2 | O00748 | 3/20 | 0.44 |
| ▸ | CES1 | P23141 | 3/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.40 |
| ▸ | TUBB | P07437 | 2/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.40 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.40 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.40 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.40 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10899485 | 0.98 | TDP1 (0.63) | LMNATDP1CES2CES1PTGS2 | |
| SCHEMBL30439628 | 0.98 | LMNA (0.64) | LMNATDP1CES2CES1PTGS2 | |
| SCHEMBL27498332 | 0.96 | TDP1 (0.65) | LMNATDP1CES2CES1MEN1 | |
| SCHEMBL30225789 | 0.96 | TDP1 (0.65) | LMNATDP1CES2CES1MEN1 | |
| SCHEMBL28297913 | 0.96 | TDP1 (0.65) | LMNATDP1CES2CES1MEN1 | |
| SCHEMBL28702570 | 0.96 | TDP1 (0.65) | LMNATDP1CES2CES1MEN1 | |
| SCHEMBL30439792 | 0.96 | TDP1 (0.65) | LMNATDP1CES2CES1MEN1 | |
| SCHEMBL93497 | 0.96 | LMNA (0.56) | LMNATDP1CES2CES1PTGS2 | |
| SCHEMBL9311873 | 0.92 | LMNA (0.53) | LMNATDP1CES2CES1PTGS2 | |
| SCHEMBL6859722 | 0.91 | LMNA (0.60) | LMNATDP1CES2CES1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679735-B | Thermoplastic molding composition based on AES rubber with low surface gloss | BAYER MATERIALSCIENCE LLC | 2012-08-22 | — | — | CN | disclosed |
| CN-101679735-A | Thermoplastic composition with low surface gloss based on AES rubber | BAYER MATERIALSCIENCE LLC | 2010-03-24 | — | — | CN | disclosed |
| WO-1997014947-A2 | CONTAINER FOR CALIBRATION FLUID | LION LABORATORIES PLC (GB) | 1997-04-24 | — | — | WO | disclosed |