Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 16/20 | 0.54 |
| ▸ | ALPG | P10696 | 1/20 | 0.46 |
| ▸ | MARS1 | P56192 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11512790 | 0.80 | IDO1 (0.56) | ALPLKMT2AIDO1 | |
| SCHEMBL31703168 | 0.77 | ALPL (0.56) | ALPLALPGMARS1MAPK1KMT2A | |
| SCHEMBL4624829 | 0.76 | NOTUM (0.52) | ALPLKMT2A | |
| SCHEMBL14069225 | 0.73 | ALPL (0.56) | ALPLALPGMAPK1KMT2A | |
| SCHEMBL6311744 | 0.71 | ALPL (0.62) | ALPLALPGMARS1MAPK1KMT2A | |
| SCHEMBL10682654 | 0.71 | ALPL (0.58) | ALPLALPGMAPK1KMT2A | |
| SCHEMBL9822966 | 0.71 | EIF4E (0.45) | ALPLMARS1 | |
| Hydrochloric Acid SCHEMBL15191228 | 0.70 | ALPL (0.56) | ALPLALPGMAPK1KMT2A | |
| SCHEMBL10049176 | 0.70 | ALPL (0.78) | ALPLALPGMARS1 | |
| SCHEMBL2558487 | 0.70 | ALPL (1.00) | ALPLALPGMARS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4613603-A | Compounds with a nitrogen-containing heterocyclic nucleus, and drugs in which they are present | SANOFI (FR) | 1986-09-23 | — | — | US | disclosed |