Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 18/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ALPG | P10696 | 1/20 | 0.52 |
| ▸ | MARS1 | P56192 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6312767 | 0.83 | KMO (0.46) | ALPLMAPK1KMT2AALPGMARS1 | |
| SCHEMBL10682654 | 0.79 | ALPL (0.58) | ALPLMAPK1KMT2AALPG | |
| Hydrochloric Acid SCHEMBL15191228 | 0.77 | ALPL (0.56) | ALPLMAPK1KMT2AALPG | |
| SCHEMBL10049176 | 0.77 | ALPL (0.78) | ALPLALPGMARS1 | |
| SCHEMBL2558487 | 0.77 | ALPL (1.00) | ALPLALPGMARS1 | |
| SCHEMBL13539279 | 0.76 | ALPL (0.76) | ALPLALPGMARS1 | |
| Hydrochloric Acid SCHEMBL14800229 | 0.76 | ALPL (0.97) | ALPLALPGMARS1 | |
| SCHEMBL28833108 | 0.76 | ALPL (0.59) | ALPLMAPK1KMT2AMARS1 | |
| SCHEMBL31703168 | 0.74 | ALPL (0.56) | ALPLMAPK1KMT2AALPGMARS1 | |
| SCHEMBL14069225 | 0.73 | ALPL (0.56) | ALPLMAPK1KMT2AALPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6903224-B2 | Substituted 1,3-oxathiolanes | BIOCHEM PHARMA INC. (CA) | 2005-06-07 | — | — | US | claimed |
| US-6897322-B2 | Method of producing 1-alkyl-3-aryl-5-difluoromethoxy-1H-pyrazoles | BASF AKTIENGESELLSCHAFT (DE) | 2005-05-24 | — | — | US | disclosed |
| US-20040059128-A1 | Method of producing 1-alkyl-3-aryl-5-difluoromethoxy-ih-pyrazoles | BASF AKTIENGESELLSCHAFT (DE) | 2004-03-25 | — | — | US | disclosed |
| EP-1358164-A1 | METHOD OF PRODUCING 1-ALKYL-3-ARYL-5-DIFLUOROMETHOXY-1H-PYRAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 2003-11-05 | — | — | EP | disclosed |
| WO-2002055504-A1 | METHOD OF PRODUCING 1-ALKYL-3-ARYL-5-DIFLUOROMETHOXY-1H-PYRAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 2002-07-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040059128-A1 | Method of producing 1-alkyl-3-aryl-5-difluoromethoxy-ih-pyrazoles | CYP2E1, CYP2F1, CYP1A1 | ALPL 2813/4885MAPK1 2135/4885KMT2A 407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.