Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.56 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.56 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 4/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.43 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3391710 | 0.80 | MAPT (0.59) | MAPTNPSR1HTTKDM4ENPC1 | |
| SCHEMBL5066695 | 0.78 | MEN1 (0.47) | MAPTNPSR1HTTKDM4ENPC1 | |
| SCHEMBL10900423 | 0.78 | ALDH1A1 (0.38) | MAPTNPSR1HTTKDM4ENPC1 | |
| SCHEMBL6093473 | 0.77 | MAPT (0.56) | MAPTNPSR1HTTKDM4ENPC1 | |
| SCHEMBL10999954 | 0.74 | MAPT (0.53) | MAPTNPSR1HTTKDM4ENPC1 | |
| SCHEMBL7761625 | 0.74 | MAPT (0.53) | MAPTNPSR1HTTKDM4ENPC1 | |
| SCHEMBL10900722 | 0.74 | MAPT (0.45) | MAPTNPSR1HTTKDM4ENPC1 | |
| SCHEMBL10706550 | 0.74 | MEN1 (0.40) | MAPTNPSR1HTTKDM4ENPC1 | |
| SCHEMBL11001735 | 0.72 | CFTR (0.39) | MAPTNPSR1HTTKDM4ENPC1 | |
| SCHEMBL10900266 | 0.72 | ALDH1A1 (0.43) | MAPTNPSR1HTTKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4616016-A | MIXTURE OF QUINALDINES, QUINOLINES, CYCLOHEXENE AMINOREDUCTONES | BASF AKTIENGESELLSCHAFT (DE) | 1986-10-07 | — | — | US | claimed |
| EP-0124752-B1 | MIXTURES OF SUBSTANCES WITH GROWTH AND OUTPUT ACCELERATING EFFECT AS WELL AS FEED AND WATERING LIQUIDS WHICH CONTAIN LOW AMOUNTS OF THESE MIXTURES | BASF Aktiengesellschaft (DE) | 1986-07-16 | — | — | EP | claimed |
| US-4510146-A | SUBSTITUTED QUINOLINE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 1985-04-09 | — | — | US | claimed |
| EP-0065192-B1 | GROWTH-PROMOTING FODDER OR DRINKING LIQUID | BASF Aktiengesellschaft (DE) | 1984-02-01 | — | — | EP | claimed |
| US-20100184804-A1 | METHODS FOR THE PREVENTION OR TREATMENT OF BACTERIAL AND FUNGAL INFECTIONS | THE GENERAL HOSPITAL CORPORATION | 2010-07-22 | — | — | US | disclosed |
| US-4616016-A | MIXTURE OF QUINALDINES, QUINOLINES, CYCLOHEXENE AMINOREDUCTONES | BASF AKTIENGESELLSCHAFT (DE) | 1986-10-07 | — | — | US | disclosed |
| US-4510146-A | SUBSTITUTED QUINOLINE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 1985-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184804-A1 | METHODS FOR THE PREVENTION OR TREATMENT OF BACTERIAL AND FUNGAL INFECTIONS | VAC14, ST14, RPL14 | MAPT 3915/4885NPSR1 4302/4885HTT 3972/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.